Neurontin generic gabapentin, lamotrigine, levetiracetam, and valproate. The study did not evaluate efficacy and safety of any these agents for the treatment of acute or chronic pain in MS patients.
In a posthoc analysis, the researchers identified 12 studies involving 541 patients and included data in 541 patients neurontin 300 mg generico during the study period from December 2001 through February 2008. Of the subjects in studies, 12.6% (n = 521) had a chronic or acute pain disorder and 8.6% (n = 49) had no pain at baseline. During the study period, investigators identified 477 subjects who reported they had pain for more than 1 drugstore australia day per week during the preceding 6 months. Of these, 6.6% (n = 189) reported being treated with a nonpharmaceutical therapy for pain, which the researchers classified as NSAIDs/acetaminophen, benzodiazepines, ibuprofen, or topical corticosteroids.
The researchers assessed association between NSAID use and pain using Tobradex generic drops the International Foundation (IPF) Global Pain Inventory Pain-Index with gabapentin generic for neurontin a global score of 4 or 5. NSAIDs are categorized into three groups: nonsteroidal anti-inflammatory drugs, prostaglandins, and drugs. Among the study population, those with a global score of 4 or 5 had a significantly reduced pain disability (relative risk, 0.33; 95% confidence interval [95% CI], 0.20 to 0.56).
For example, use of NSAIDs pain (n = 477), for more than 1 day per week (n = 189), on a daily basis (n = 8.06%), and on a monthly basis (n = 30.96%) significantly reduced pain disability at 12 weeks or 1 year compared with pain in the non-nursing control group (P <.01). The reduction in pain disability associated with nonsteroidal anti-inflammatory drugs for pain was even more pronounced (P <.001).
"The results showed that use of NSAIDs for pain appears to be associated with a reduction in pain disability for MS patients during a 12-to-24-month period," said study leader Christopher M. Sorensen, MD, PhD, assistant professor of dermatology at Emory University School of Medicine. "A limitation this study is that we were unable to evaluate the efficacy of non-pharmaceutical interventions for pain in MS patients."
"There are multiple approaches to treating high pain levels in MS patients. Although the objective of this study is to understand the relationship between pain Neurontin 270 pills 20 mg - 295.48$ in MS and an NSAID use disorder, the results of current study do not justify the use of non-pharmaceutical interventions to treat pain in MS patients," added co-investigator Elizabeth A. Huggins, PhD, professor of neurology at Emory University School of Medicine.
"This is a preliminary assessment of the possible clinical utility non-pharmaceutical interventions to treat chronic pain in patients with MS, and additional studies are needed to further examine the efficacy of non-pharmaceutical treatments for pain and their potential effects on MS disease progression."
The study was funded by National Institutes of Health (grant R01MS078359), the Leona M. and Harry B. Helmsley Charitable Trust, and an unrestricted clinical trial contract with Pfizer.
The paper, "Non-Pharmaceutical Interventions for Pain in"
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